The role of photodynamic therapy (PDT) physics
نویسندگان
چکیده
منابع مشابه
Photodynamic therapy (PDT)
Photodynamic therapy (PDT) is a comparatively novel therapeutic method involving a safe light source and a light-sensitive substance, termed as photosensitizers (PSs), such as methylene blue (MB), toluidine blue (TBO), sulfonated aluminum phthalocyanine, chlorine derivatives, nontoxic indocyanine green (ICG), and curcumin (CUR). (1) The combination of a nontoxic PS with low-intensity visible li...
متن کاملPhotodynamic Therapy (PDT): PDT Mechanisms
Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in oncology a photosensitizing agent is applied and then activated by a specific wavelength and energy of light. This light energy in the presence of oxygen will lead to the creation of the photodynamic reaction which is cyto and vasculo toxic. This paper will review the mechanisms of action of PDT and how t...
متن کاملAnimal models for photodynamic therapy (PDT).
Photodynamic therapy (PDT) employs non-toxic dyes called photosensitizers (PSs), which absorb visible light to give the excited singlet state, followed by the long-lived triplet state that can undergo photochemistry. In the presence of ambient oxygen, reactive oxygen species (ROS), such as singlet oxygen and hydroxyl radicals are formed that are able to kill cancer cells, inactivate microbial p...
متن کاملPerspectives on the role of photodynamic therapy (PDT) in the treatment of pancreatic cancer
Photodynamic therapy (PDT) is a non-invasive procedure involving a photosensitizing agent that is activated by light to produce reactive oxygen species (ROS) that selectively destroy tumor cells. In recent years, PDT has been used in the treatment of pancreatic cancer (PC). The anti-tumor effects of PDT include three main mechanisms: direct tumor cell death (necrosis, apoptosis, and autophagy),...
متن کامل[Use of nanoparticles (NP) in photodynamic therapy (PDT) against cancer].
Nanotechnology is a promising interdisciplinary field for developing improved methods of diagnosis and treatment of different diseases, including cancer. Give their optical, magnetic, and structural property, the nanoparticles have been proposed to be use in the development of unconventional treatments for cancer such as photodynamic therapy (PDT). In PDT, a photosensitizing agent is used that ...
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ژورنال
عنوان ژورنال: Medical Physics
سال: 2008
ISSN: 0094-2405
DOI: 10.1118/1.2937440